ArthroVet HA is a preparation for the prevention and improvement of dogs and cats with articular cartilage and joint dysfunction. It is recommended both for young animals during intensive growth and for older animals with degenerative joint disease (osteoarthritis). The preparation contains three main components of glucosaminoglycans (GAG) of the intercellular matrix of articular cartilage: glucosamine, chondroitin (in the form of sulfate) and hyaluronic acid. Increasing their supply in the animal's diet can improve the synthesis of endogenous GAGs (glucosamine) and increase the water content of joint cartilage (chondroitin and hyaluronic acid), which improves their elasticity. The beneficial effects of glucosamine and chondroitin sulfate in dogs with osteoarthritis were confirmed in a randomized double-blind clinical trial (osteoarthritis) by McCarthy et al. (2007). In these studies, dogs treated with glucosamine and chondroitin sulfate had clinically significant improvements in pain scores, limb weight, and disease severity. The ArthroVet HA preparation is also one of the first on the market to contain hyaluronic acid, which is absorbed orally (Balogh et al., 2008), and the use of a mixture of glucosamine, chondroitin and hyaluronic acid ensures greater effectiveness of the preparation. than using a preparation containing only glucosamine and chondroitin in the treatment of patients with degenerative changes in the knee joint (Bucci et al., 2005). Vitamin C supports the production of articular cartilage extracellular matrix proteins and acts as a coenzyme in collagen synthesis. Ascorbic acid (vitamin C) is a coenzyme of prolyl and lysyl hydroxylase, ie the main enzymes of collagen synthesis. In in vitro studies, ascorbate and ascorbic acid increased the synthesis of proteins and proteoglycans in chondrocytes of articular cartilage (Ameye and Chee, 2006). For this reason, ArthtoVet HA supplement contains active ingredients with a scientifically proven mechanism of joint support in osteoarthritis. , colloidal silicon dioxide 5 mg, Analysis: protein 20.83%, fat 3.9%, ash 0.82%, fiber 19.24%, moisture 3% Dosage: 1 tablet per 20 kg of body weight. with a veterinarian
